Publications

Dr. Laura Dugan’s expertise in the field of Central Nervous System (CNS) diseases is widely acknowledged. She has been published extensively in all of the major peer-reviewed journals on the subject. Below is a selection of papers relating to her work in CNS and C3:
  • Carboxyfullerene neuroprotection postinjury in Parkinsonian nonhuman primates.
  • New data strongly support further development of C3 as a promising therapeutic agent for Parkinson disease.
  • Development of a fullerene-based synthetic superoxide dismutase mimetic (C3) for treatment of Central Nervous System (CNS) diseases
  • Enhancement of Apoptosis in Cerebral Endothelial Cells by Selected Inflammatory Signals
  • Interleukin-6 Mediates the Increase in NADPH-Oxidase in the Ketamine Model of Schizophrenia
  • Ketamine-Induced Loss of Phenotype of Fast-Spiking Interneurons Is Mediated by NADPH-Oxidase
  • SOD Activity of carboxyfullerenes predicts their neuroprotective efficacy: a structure-activity study
  • A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice
  • Fullerene-based antioxidants and neurodegenerative disorders
  • IL-6 Mediated Degeneration of Forebrain GABAergic Interneurons and Cognitive Impairment in Aged Mice through Activation of Neuronal NADPH Oxidase
  • Carboxyfullerenes as neuroprotective agents
  • Mechanisms of Neuroprotection by C60 Derivatives

Content:

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Click to view our video of Dr. Dugan, our chief researcher, and Ed Handler, our executive chairman, as they discuss C3, Fullerene Therapeutics’ novel compound.

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